Los Angeles -LRB- CNN -RRB- -- Johnny Depp brought the biggest star power to the MTV Movie Awards on Sunday , taking the stage to play guitar while he was honored for his acting career .

Aerosmith 's Joe Perry and Stephen Tyler presented the MTV Generation Award to Depp , while The Black Keys played a song with Depp on guitar .

`` Johnny Depp is a rock star in the world of movies , '' Tyler said .

Perry called him `` a gutsy actor , a gutsy musician , a gutsy artist with passion . ''

`` He 's legitimately great on guitar , '' Black Keys ' lead singer-guitarist Dan Auerbach told CNN backstage after the performance .

Otherwise , the two-hour telecast was filled with penis one-liners and sight gags interrupted occasionally with the presentation of gold-plated popcorn box trophies for achievements including `` best on-screen dirt bag . ''

Host Russell Brand set the mood with an opening monologue that included no less than four jokes about the male reproductive organ . The person in charge of censoring foul language was kept busy through the show .

`` The Twilight Saga : Breaking Dawn - Part 1 '' won the highest honor , movie of the year , in the fan voting that continued online even as the show was underway .

`` Twilight '' stars Robert Pattinson and Kristen Stewart won for best kiss , an honor they received for the previous installment as well .

`` Thanks , you guys , for giving us best kiss again , '' Stewart said .

`` The Hunger Games '' claimed four acting awards , including best male and female performances for Josh Hutcherson and Jennifer Lawrence , respectively . The pair also won for `` best on-screen fight . ''

`` Hunger Games '' actress Elizabeth Banks was voted best on-screen transformation for her portrayal of District 12 escort Effie Trinket .

`` Harry Potter and the Deathly Hallows : Part 2 '' took the best cast trophy .

`` Bridesmaid '' star Melissa McCarthy won for best comedic performance . She and her ensemble of castmates were honored for `` best gut-wrenching performance , '' for the food poisoning in the dressing room scene .

MTV 's breakthrough performance award went to actress Shailene Woodley for her role in `` The Descendants , '' George Clooney 's Oscar-nominated film .

`` Right now , I have no idea what 's going on , '' Woodley said backstage . It would take time to digest the significance of her new gold popcorn trophy , she said .

A seemingly sober Charlie Sheen paid tribute to `` Project X , '' declaring it an instant cult classic . It had all the ingredients of a party movie : Beer , babes , more beer and destruction , he said .

`` Finally a movie that captures what 's going on in my head 24 hours a day , '' Sheen said .

Jennifer Aniston gloated over winning for `` best on-screen dirt bag '' for her role in `` Horrible Bosses . ''

`` Do you know how long I 've have tried to have someone let me unleash my on-screen dirtbag ? '' she said in her acceptance speech .

During a more serious part of the show , actress Emma Stone was brought to tears after she accepted the MTV Trailblazer Award . It is a recognition of her unusual path to stardom .

She told her teenaged fans to harness their own originality . `` A lot of times , it 's what makes you great , '' Stone said .

The best music trophy was handed to LMFAO for `` Party Rock Anthem , '' heard in `` 21 Jump Street . ''

@highlight

`` Johnny Depp is a rock star in the world of movies , '' Aerosmith 's Steven Tyler says

@highlight

`` The Twilight Saga : Breaking Dawn - Part 1 '' wins movie of the year

@highlight

`` The Hunger Games '' claims four acting awards

@highlight

`` Harry Potter and the Deathly Hallows : Part 2 '' takes the best cast trophy